Obsessive Compulsive Disorder as a Rare Manifestation of Wilson’s Disease
Published: December 1, 2022 | DOI: https://doi.org/10.7860/JCDR/2022/60026.17203
Ishani Roy, Debasish Sanyal
1. Postgraduate Trainee, Department of Psychiatry, Kali Pradip Chaudhuri Medical College and Hospital, Kolkata, West Bengal, India.
2. Professor and Head, Department of Psychiatry, Kali Pradip Chaudhuri Medical College and Hospital, Kolkata, West Bengal, India.
Correspondence
Dr. Ishani Roy,
Flat 26, 10 Judges Court Road, Alipore, Kolkata-700027, West Bengal, India.
E-mail: ishaniroy10@gmail.com
Wilson’s disease is a rare autosomal recessive disorder of copper metabolism, that causes an impairment of cellular copper transport. An individual’s inability to excrete excess copper in bile leads to accumulation of copper in organs like the brain, liver and cornea. It can manifest with symptoms of hepatic impairment and liver failure. It can also present with neurological symptoms like rigidity, gait disturbances, dystonia, dysarthria and chorea. Frequently certain psychiatric manifestations have been reported like mood changes, personality changes, cognitive impairment, phobias, psychosis, anxiety, impulsive and compulsive behaviours . It’s rare for a Wilson’s disease patient to present with only Obsessive Compulsive Disorder (OCD). In the present case report, a 15-year-old male presented in the Outpatient Department with complaints of repetitive intrusive thoughts that he was unable to voluntarily control and compulsions of washing and preoccupation with checking and symmetrical organising with a deteriorating scholastic performance. The only positive findings were Kayser-Fleischer rings, low serum ceruloplasmin and mild cerebellar atrophy. The patient started showing symptomatic improvement with pharmacological treatment comprising of zinc, D-penicillamine, and fluoxetine and diet modification.
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